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Welcome to BioNEDD Lab

Biopolymers and Nanoengineering for Drug Delivery and Molecular Imaging

      Our research objective is to develop polymeric drug delivery systems (DDSs) that can efficiently deliver anticancer drug to cancer cells. Polymers used for these DDSs are biocompatible and biodegradable. DDSs can be prepared in millimeter, nanometer and molecular scale. For the millimeter scale, the research aim is to develop intratumoral implantations that can be injected directly insides tumors. Anticancer drugs that are kept inside will release and kill cancer cells.
     

      For the nanoscale, we develop magnetic nanoparticles that can be detected by MRI once injected inside the body. Not only to visualize cancer cells in vivo but these nanoparticles can also selectively deliver anticancer drugs to these cancer cells. For the molecular scale, anticancer drugs are chemically conjugated to the polymer chain to enhance the cancer cell uptake and reduce the side effects of these drug

Research Focus

  1. Multifunctional polymeric nanoparticles as cancer targeted, SPECT and MRI imaging probes.
  2. In situ solidifying, intratumoral injectable polymer implants for brain cancer chemotherapy.
  3. Minimally invasive polymer rods for intratumoral implantable liver cancer chemotherapy.
  4. Antibacterial coating of medical devices

Selected Publications

Preparation and in vitro characterization of SN-38-loaded, self-forming polymeric depots as an injectable drug delivery system (J. Pharm. Sci.)

 

Tri-component copolymer rods as an implantable reservoir drug delivery system for constant and controllable drug release rate (J. Mat. Sci.: Mat. Med.)

Open Position& Scholarship!

We currently have available positions for research assistant and scholarship for graduate program in Biomedical Engineering at Mahidol University.

We are recruiting Ph.D. students for Royal Golden Jubilee (RGJ)  scholarship

 

Latest News

02/2015-Miss.Hathaichanok Phuengkham received the Ph.D. scholarship of Sungkyunkwan University from The Royal scholarships under the patronage of H.R.H. Princess Maha Chakri Sirindhorn

07/2014- Our PI gave a lecture at 2014 Anual Meeting and International Conference of the Korean Society of Pharmaceutical Science and Technology, Korea

08/2014-
Mr. Ketpat Vejjasilpa received the Ph.D. Scholarship of NANOTEC from The Office of The Civil Service Commission, Thailand

6-11/07- The 2014 IUPAC World Polymer Congress or MACRO 2014 Chiangmai, Thailand

Please feel free to contact Assist. Prof. Norased at norased.nas[at] mahidol.ac.th, if you have any question or comment .

 

Current Project

 

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Polymeric Implant
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Medical Imaging
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Nanoscale DDS
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Antibacterial Coating